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Keep an eye on Intently (1)phenobarbital will minimize the level or effect of fentanyl transmucosal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead to the reduce in fentanyl plasma concentrations, lack of efficacy or, perhaps, progress of

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